Document Type
Poster
Publication Date
Summer 2018
Abstract
Isothiocyanates (ITCs) are bioactive products found in several plants belonging to the Brassicaceae family, and are produced as defense upon disruption of the tissue by herbivores or pathogens, but in humans they have shown anti-cancer and anti-inflammatory properties.
Although we know gut microbes can hydrolyze GSL into ITC, the mechanism is not known. With improved detection methods, the aim of this experiment is to explore whether the gut microbial myrosinase β-glucosidase found within the genome of E. coli Nissle 1917 can hydrolyze glucosinolates (GSLs) into detectable ITCs.
Rights
Copyright is owned by the creators of this work.
Recommended Citation
Isaiz, Juan; Liu, Xiaoji; and Miller, Michael J., "Production of Bioactive Isothiocyanates by Bacterial Myrosinase" (2018). PRECS student projects. 20.
https://spark.parkland.edu/precs_student/20
Included in
Dietetics and Clinical Nutrition Commons, Environmental Sciences Commons, Genetics and Genomics Commons
Comments
Research for this project was conducted in cooperation with the Department of Food Science and Nutrition at the University of Illinois at Urbana-Champaign.
Financial support was provided by the National Science Foundation under grant #NSF REU 1559908/1559929, as part of the Phenotypic Plasticity Research Experience for Community College Students, through the University of Illinois at Urbana-Champaign Institute for Genomic Biology and Parkland College.