Role of Age and Sex in the Effects of Repeated Methamphetamine Exposure on Hedonic Tone in Sprague Dawley Rats

Authors

Cameron Lewis, City Colleges of Chicago - Malcolm X College
Conor Strumberger, University of Illinois at Urbana-Champaign
Joshua M. Gulley, University of Illinois at Urbana-Champaign

Document Type

Poster

Publication Date

Spring 2023

Abstract

Anhedonia is defined as a reduced or complete loss of pleasure from a previously pleasurable stimulus, and it is comprised of two dimensions:

• Hedonic anhedonia consists of a distinct loss of pleasure in consumption of a normally pleasurable stimulus.
• Motivational anhedonia involves the goal directed behavior to obtain a reward.

Withdrawal induced anhedonia following use of methamphetamine (METH) is thought to contribute to relapse behaviors^1,2 . The anhedonic effects of drug withdrawal largely depend on dose, frequency, and the duration of drug exposure^4,5,6.

The role of sex and age of exposure in this context has yet to be elucidated.

Rights

Copyright is owned by the creators of this work.

Recommended Citation

Lewis, Cameron; Strumberger, Conor; and Gulley, Joshua M., "Role of Age and Sex in the Effects of Repeated Methamphetamine Exposure on Hedonic Tone in Sprague Dawley Rats" (2023). PRECS student projects. 104.
https://spark.parkland.edu/precs_student/104