Efficacy and Evolutionary Dynamics of 222 nm Far-UVC Against Vibrio cholerae

Authors

• Kadicha Madakimova, Berkeley City College
• Angus Wu, University of Illinois at Urbana-Champaign
• Nkrumah Grant, University of Illinois at Urbana-Champaign

Document Type

Poster

Publication Date

Summer 2026

Abstract

The Far-UVC light at 222 nm wavelength (UV222) is one of the emerging methods of disinfection of bacteria in public spaces such as hospitals and labs.

• Does not penetrate human skin and does not cause harm to eyes making it a safer alternative to conventional UV systems.

• Primarily targets proteins preventing regrowth and repair pathways.

However, the potential for bacterial adaptation following sublethal UV222 exposure remains largely unknown.

Central question: How does QS transcriptional state influence the efficacy and resistance profile of V. cholerae to UV222 nm irradiation?

Hypothesis: Qurom-sensing transcriptional state determines V. cholerae susceptibility to UV222 nm UV irradiation by altering the expression of stress response, DNA repair and cell envelope maintenance pathways.

Rights

Copyright is owned by the creator of this work.

Recommended Citation

Madakimova, Kadicha; Wu, Angus; and Grant, Nkrumah, "Efficacy and Evolutionary Dynamics of 222 nm Far-UVC Against Vibrio cholerae" (2026). MICRO-CCS student projects. 27.
https://spark.parkland.edu/micro_ccs_student/27